Achondroplasia.
Achondroplasia. Body of foetus one half of which has been dissected to show skeleton. Head is disproportionately large, constituting one third instead of one fourth total length, partly due to internal hydrocephalus. Face is relatively small and base of skull short owing to premature synostosis of the basal structures. All that portion of the skull which arises in membrane has developed normally and is, therefore, greatly exaggerated. The limbs are short and thick, the hands spatulate and the fingers spread out like the spokes of a wheel. The long bones are short and thick with relative enlargement of the epiphyses owing to the small size of the shafts. HISTORY: J.B.S Trans. Path Soc. XXXV 464.

Middlesex Hospital

LDUCPC-MX.C.3

C.3

UCL Pathology Collections